Trade card advertising Ayer's Pills and Ayer's Sarsaparilla featuring eight children holding up a sign that reads: "'The Little Favorites' Ayer's Pills. Sugar Coated." Most are casually dressed save for the child farthest in the background on the right-hand side who is wearing a peach-colored headwrap of some sort. In front of her is a boy holding a white cat. There is a girl wearing a flowered wreath in her hair towards the front of the group. The girl next to her is holding a red item in her left hand. Behind the group are grasses and leaves. The back has a poem and describes the curative properties for the Ayer's products advertised.