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An illuminated and illustrated manuscript of the Chirurgia magna, or great surgery, by Guy de Chauliac. Attempting in the Chirurgia to collect the best medical ideas of his time, he compiled sources from Arabic and Greek writers, including Rhazes, Avicenna, Hippocrates, Aristotle and others. Guy wrote the first text of the Chirurgia in Latin at Montpellier, in approximately 1363. This text was published in many editions and remained the authoritative text on surgery through the seventeenth century. It consists of 181 pages of English black letter in double columns and lines lightly ruled in red. It is ornately illuminated in gold and silver with finely decorated floral borders and large floriated initials, heightened with gold leaf. The manuscript includes 24 drawings of surgical instruments. The calf binding dates to Henry VIII’s reign or to the Elizabethan era. The original brass and leather clasps are engraved with stars and lion heads. There has been dispute about the manuscript’s date, with authorities dating it between the late 14th and second half of the 15th century. The manuscript was sold with the Streeter collection to the New York Academy of Medicine in 1928.