This is the fourth edition of the Fasciculus and the third printed in Venice (after 1491 and 1493 editions both also by the Brothers Gregorii). It was printed in Latin and reset in Gothic type. In this edition, the page is shorter by four lines, resulting in plates that are too large and in many cases, clipped by the binder. This is the earliest edition with a real title page. Our copy lacks the urinoscopic consultation plate and the plate showing the circle of urine glasses.